L-Theanine and Alcohol Withdrawal: How It Works

In this article, we’ll discuss L-theanine and alcohol withdrawal. Not all supplements for recovery produce immediate effects, but this one stands out for its ability to induce immediate relaxation. Months after I quit drinking, I discovered that this supplement helped to end my post-acute withdrawal symptoms, including:

  • Insomnia
  • Restlessness
  • Anxiety
  • Nervous exhaustion

l-theanine and alcohol

As soon as I quit drinking, I began taking a multivitamin, extra B-vitamins, and fish oil. While these basic nutrients helped, I did not feel totally stable until I discovered these amino acids L-glutamine and DLPA.

After reading this article, you will have a clear understanding of the benefits of using this amino acid (including post-acute withdrawal). You will also know where to obtain the highest quality supplements and what dosage is considered safe and effective.


l-theanine and alcohol withdrawal

L-theanine is an amino acid primarily known for its relaxing effects. It is contained naturally in green tea, helping to balance out the stimulating and jittery effects of caffeine. Over the past decade, these supplements have become popular among people interested in natural health and nootropics.

This amino acid reduces levels of cortisol, which is a stress hormone, and has been found to reduce abrupt blood pressure spikes in people who are experiencing stress.

As a dietary supplement, it can help to relieve the following issues:

  • Anxiety
  • Insomnia
  • Depression
  • Mood swings

It is similar in structure to a stress chemical in the brain called glutamate. Glutamate causes increased electrical activity in the brain, a state that anyone who has experienced withdrawal can relate to. When the amino acid plugs into glutamate receptors, it prevents glutamate from binding to these receptors and causing panic and jitters.

It may have a long-term protective benefit for brain cells since many neurodegenerative conditions have been linked to excitotoxicity caused by high glutamate levels. (source)

l-theanine and alcohol withdrawal

This is an analogue of another amino acid known as L-glutamine, and can also serve as a building block for natural GABA production. Ingesting it increases the brain’s natural supply of GABA. Since GABA and glutamate balance each other out in the brain, more GABA activity results in less glutamate activity.

Scientific research indicates that this amino acid also boosts levels of other important chemicals in the brain:

  • Serotonin – Associated with feelings of confidence and relaxation
  • Dopamine – Associated with reward, motivation, and learning
  • Acetylcholine – Associated with cognitive function and mental sharpness
  • Brain-Derived Neurotrophic Factor (BDNF) – Involved in the generation of new neurons and new connections between neurons

l-theanine and alcohol withdrawal

Because withdrawal largely results from the depletion of these natural brain chemicals, it makes intuitive sense that supplementation can help to alleviate symptoms of withdrawal.

As mentioned above, many people enjoy this amino acid simply by drinking green tea. However, the beneficial effects of it are more pronounced when this natural compound is isolated from caffeine and taken in supplement form.

L-Theanine for Alcohol Withdrawal

l-theanine for alcohol withdrawal

This amino acid exerts subtle effects on a range of neurotransmitters, but its most noticeable effect is relaxation. This is the case because it acts most powerfully on the brain’s GABA and glutamate system. In this section, we will review the importance of GABA and glutamate for the person who has recently quit drinking and is experiencing withdrawal.

GABA (gamma-aminobutyric acid) is an inhibitory neurotransmitter that dampens activity in the brain and causes a sensation of relaxation. GABA is perhaps the most important neurotransmitter involved in addiction, and also intuitively the easiest one to understand.

Most drinkers subjectively understand the experience of it influencing their GABA receptors. Up to a certain point, the outside world seems to slow down to a manageable pace.

l-theanine and alcohol

People who drink to relax are essentially drinking to activate their GABA receptors.

Many people start drinking excessively because of an inherent deficiency in GABA production. Once dependence occurs, natural GABA production is guaranteed to decline – even after a person stops drinking!

This is the case because the brain compensates for the repeated presence of alcohol by decreasing natural GABA production.

While it impersonates GABA, it indirectly releases endorphins, dopamine, serotonin, and several other “feel good” neurotransmitters. All of these effects blend into the state of mind that we know as intoxication.

During withdrawal, GABA levels plunge (along with levels of these other feel-good chemicals). This is the natural result of having adapted to the presence of drinking by turning the dial down on natural GABA production.

When GABA levels fall, glutamate surges – causing hyperexcitability, nervousness, panic attacks, insomnia, and even hallucinations.

Now you understand why this is uniquely suitable for helping to soothe withdrawal symptoms like anxiety and insomnia. In the proper dosage (more on this below), it can provide instant relief from these symptoms – and it is gentle enough to be consumed daily for extended periods of time.

With all of this said, this amino acid is not potent enough to mitigate severe cases of withdrawal. If you are experiencing hallucinations or seizures, your best bet is to get professional care immediately. Doctors will likely prescribe a powerful benzodiazepine such as Ativan. After detox, amino acids can be very helpful to prevent post-acute withdrawal symptoms.

My Experience

I did not discover this amino acid until months after I’d quit drinking. Because I had a very severe case of addiction, I was admitted to detox and given a tapered dose of benzodiazepines for nearly two weeks.

It took me months of research to identify natural compounds for withdrawal. While I was done with the acute phase of withdrawal, I had post-acute withdrawal symptoms – including intermittent bouts of anxiety and insomnia – for many months after I quit drinking.

I recall that when I first began taking it, my nightly routine consisted of chamomile tea. I noticed that the addition of 50-100mg really helped me to relax and cut down on the amount of time I needed to fall asleep.

I continued taking it for about 3 months to help me wind down in the evenings. At the time, I had not even studied the basic biochemistry that we have covered in this article. I simply knew that I felt better – more relaxed, more positive – when I took it in the evenings.

Over time, I added additional supplements to my regimen, keeping what worked for me and discarding what did not work. This process of trial and error led to many epiphanies and a steadily increasing sense of well-being. Eventually, I achieved mental stability and even stopped missing it.

Looking back, it’s frustrating for me to think about how long it took me to discover natural remedies for post-acute withdrawal. The good news is that you don’t have to wait as long as I did to fix your neurotransmitter imbalances and move on with your life!


l-theanine for alcohol withdrawal

Scientific research supports the use of this amino acid for withdrawal:

  • Reduces the concentration of alcohol in the blood of drinkers and prevents alcoholic liver injury by enhancing the antioxidant capability of liver cells. (source, source)
  • Addiction involves an increase in the number of glutamate receptors, which amino acids like Can fill to help prevent withdrawal symptoms. (source)
  • In addition to its well-established relaxing effects, it has antipsychotic and antidepressant effects. (source)
  • Crosses the blood-brain barrier and exerts a variety of effects, including increasing GABA activity, modulating serotonin and dopamine, increasing brain-derived neurotrophic factor (BDNF), and increasing cognitive performance through its actions on NMDA receptors. (source)
  • 8 weeks of administration to depressed patients produced multiple beneficial effects on depressive symptoms, anxiety, sleep disturbances, and cognitive impairments. (source)
  • A study in mice found that this amino acid exerts a neuro-protective effect that is mediated by GABA-A receptors. (source)
  • Can help with nicotine withdrawal by significantly inhibiting the rewarding effects of nicotine. (source)


If you have recently quit drinking, 50-200 mg per day of this high-quality supplement can help to alleviate the anxiety and insomnia that often accompany protracted (post-acute) withdrawal.

People who begin supplementing with this amino acid usually begin to feel noticeably better. Depending on the severity of the drinking problem or gut damage that inhibits absorption, it may take a few weeks before feeling any positive effects from supplementation.

When I finally learned about this, I took 100mg Suntheanine chewable tablets. This brand works very well, but I always had to brush my teeth afterwards because the chewables got stuck in my back molars.

If I had to do it all over again, I would simply take Calm Support, which contains 80mg per serving and, if taken as directed, 160mg per day.

This dosage will be effective for the vast majority of people who are experiencing mild to moderate anxiety or insomnia due to withdrawal.

Always consult with your doctor before beginning new supplements or lifestyle changes.


I hope that you’ve enjoyed this article. I will continue to be on the lookout for new supplements that hold promise for enhancing recovery.

My drinking days are long gone. I live an exciting lifestyle that revolves in large part around optimizing my body and brain. There is a definite learning curve here, and I know that trial and error with supplementation can be frustrating.

If you’ve recently quit drinking, frame early recovery as your own individual journey and enjoy the ride. In the meantime, be sure to optimize your own lifestyle by integrating some GABA-enhancing lifestyle strategies into your daily routine:

  • Work out daily
  • Get better sleep
  • Clean up your diet
  • Take yoga classes
  • Get a Swedish massage

If you have any questions about L-theanine and alcohol withdrawal, please leave them in the comment box below.

Hierarchy of Alcohol Recovery


What can you not take with it?

Since this amino acid relaxes the nervous system, it may be counterproductive to take it along with stimulant drugs. It may also lower blood pressure, so talk to your doctor before taking it along with blood pressure medications. Overall, it is a safe amino acid with few side effects.

Is L-Theanine bad for your liver?

Research shows that it protects the liver, especially against intoxicated liver injury (source). This amino acid is not known to be harmful to the liver. If you’re looking for a supplement to support liver health, check out milk thistle.

Does it increase serotonin?

It boosts GABA activity and has also been found to slightly increase serotonin and dopamine. It does not increase serotonin as powerfully as the supplements 5HTP or L-Tryptophan.

Please review this post!



The information we provide while responding to comments is not intended to provide and does not constitute medical, legal, or other professional advice. The responses to comments on fitrecovery.com are designed to support, not replace, medical or psychiatric treatment. Please seek professional care if you believe you may have a condition.

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3 years ago

Chris, I heard you the other day on recovery elevator. I love your system as it makes perfect sense. I also bought your book drinking sucks. I love how you teach and explain everything about biochemistry and how it relates to alcohol recovery. I was in AA eating donuts and coffee and wondering why I was feeling terrible and struggling with cravings haha.

Matthew Sapp
Matthew Sapp
4 years ago


Did you have any crazy symptoms after quitting? I’m having insomnia, headaches And some BP problems, been 3 days now

Ming Lee
Ming Lee
4 years ago

I’m not sure doses that low would be enough. Glutamate is extremely, extremely high in alcoholics. Especially first thing in the morning. Which is why ultimate alcoholics drink from the moment they wake up. Taurine has a similar effect. They should be taken in conjunction. In extreme cases, even taking GABA straight up will help since by the time you’re a raging alcoholic, your BBB for sure is shot. If still an alcoholic: 4 grams Taurine, 2 Grams l-theanine (which is a lot) in the morning or whenever the alcoholic wakes up in the morning, i.e. 2am, 3am, 4am. Whenever… Read more »

Dale Stringham
Dale Stringham
4 years ago
Reply to  Ming Lee

Thank you Ming. 3 grams of L-thianine saved me a ride to the ER for treatment of acute alcohol withdrawal.

3 years ago
Reply to  Dale Stringham

Don’t you get hooked on L theanine too. Hard to get off also?

3 years ago
Reply to  Chris Scott

I have with someone tapering off benzodiazepines, they took l theanine and now hard to get off. You know of anything to help with benzo withdrawals? Also, why does alcohol bother benzo’s?

Mathew Vance
Mathew Vance
3 years ago
Reply to  Ming Lee

Would taking Gaba supplement be better than taking this?